Rotarod Apparatus With Acceleration Mode

“To evaluate drug effects on motor coordination, balance and motor learning in rodents”
Rotarod test is widely used to evaluate the effect of drug on motor coordination, balance and motor learning in rodents. The principle of this test is that rats or mice are first trained to walk on a rod rotating at a certain speed. Once the animals have learned this, the effect of a test-compound on their motor performance is evaluated. Animals experiencing impaired motor coordination are unable to cope with the rotating rod and will drop off when the rotation speed exceeds their motor coordination capacity. When the animal drops from rod safely into its own lane, the time latency to fall is
automatically recorded.

Features

• Same instrument can be used for mice as well as rat just by changing the rotor
• Five compartment model
• Three modes of operation (Normal /Acceleration 1/ Acceleration 2)
• Animal selection facility (Mice/Rat)
• Forward & reverse direction of rotation
• Facility of compartment coding (001 to 999)
• Individual lane timers (0-999.9sec) with resolution of 0.1s
• Precise data of falling time, falling speed and distance travelled
• Electronic rod speed adjustment- constant speed (0.1 to 80.0 RPM)
• Password protected software and admin features
• Software for data collection & report generation
• Calibration report generation facility in the software
• Graphical presentation of data
• Provision to add experiment Title & comment
• Data can be converted to excel & Pdf file for further analysis
• Normal Mode:
  Fixed speed selectable from 0.1 to 80 rpm can be set.
• Acceleration Mode I:
  User can set the speed to be achieved in selected acceleration time starting from 0 rpm. For example, if user sets End spand acceleration time as 60 sec then, rotor will start from 0 rpm; individual lane timers will also start same time and rotor 40 rpm speed in 60 seconds. Once rotor achieves 40 rpm, it will continue at 40 rpm up to the cutoff time.
• Acceleration Mode II:
  User can set the speed to be achieved in selected acceleration time starting from 0 rpm. Lane timers will start at the time rotor achieves the speed of 1/10th of the End Speed. As the animal falls, time measurement of the corresponding lane wil For example, if user sets End Speed as 40 and acceleration time as 60 sec then, rotor will start from 0 rpm and will achiev End speed as 4rpm. Rotor will keep rotating at 4rpm and as user selects Start key, individual lane timers will start and rotreach 40 rpm speed in 60 seconds. Once rotor achieves 40 rpm, it will continue at 40 rpm up to the cutoff time

BROCHURE :